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Tru Niagen® 300mg
Tru Niagen® 300mg
Tru Niagen® 300mg
Tru Niagen® 300mg

Our foundational daily serving of 300mg, known to boost and sustain NAD+ levels to over 50% in most individuals with daily use. Support your cellular energy production and support cellular repair with Niagen®, our award-winning, superior NAD+ precursor.

Tru Niagen is one of the most well-researched NAD+-boosting supplements available. Supports resilience against daily stressors and the natural aging process at the cellular level. Increase your NAD+ levels to support heart, brain, muscle, and whole-body health for enhanced vitality and healthy aging.


Tru Niagen 300mg won the Consumer Choice Award, voted as a top supplement for those seeking a trusted solution for everyday wellness and cellular vitality.
Tru Niagen 300mg earned the prestigious "Most Beloved Brand" title in 2023, celebrating our trusted role in enhancing wellness through cellular health support.
Niagen was honored as the 2024 Healthy Aging Ingredient of the Year, underscoring our ingredient’s proven ability to promote long-term cellular resilience.

 

Tru Niagen® 300mg

The original—boost vital NAD+ levels by over 50% with our foundational recommended daily serving. Get the details.

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Capsules 30 90 180
Monthly Cost $50.40 $135.20 $249.60
Price Per Serving $1.68 $1.50 $1.38
Savings $12.60 $33.80 $62.40
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Capsules 30 90 180
Monthly Cost $63.00 $169.00 $312.00
Price Per Serving $2.10 $1.88 $1.73
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Our foundational daily serving of 300mg, known to boost and sustain NAD+ levels to over 50% in most individuals with daily use. Support your cellular energy production and support cellular repair with Niagen®, our award-winning, superior NAD+ precursor.

Tru Niagen is one of the most well-researched NAD+-boosting supplements available. Supports resilience against daily stressors and the natural aging process at the cellular level. Increase your NAD+ levels to support heart, brain, muscle, and whole-body health for enhanced vitality and healthy aging.


Tru Niagen 300mg won the Consumer Choice Award, voted as a top supplement for those seeking a trusted solution for everyday wellness and cellular vitality.
Tru Niagen 300mg earned the prestigious "Most Beloved Brand" title in 2023, celebrating our trusted role in enhancing wellness through cellular health support.
Niagen was honored as the 2024 Healthy Aging Ingredient of the Year, underscoring our ingredient’s proven ability to promote long-term cellular resilience.

 

Whole-body benefits

From your daily routine to your biggest goals, Tru Niagen powers your cellular health, helping you thrive.

Cellular HealthBrain HealthHeart HealthMuscle HealthLifestyle Stress Management*‡
Cellular Health
Cellular energy and DNA repair

Increases blood NAD+ levels

Brain Health
Supports brain health

NAD+ helps energy metabolism

Heart Health
Supports heart health

NAD+ helps support biological function

Muscle Health
Cellular performance and repair

NAD+ can support healthy tissue formation

Lifestyle Stress Management*‡
Mitigate the effect of stressors

Daily stressors can deplete NAD+. Replenish NAD+ to support your health.

Backed by gold standard science, quality, and safety

Efficacy backed by peer-reviewed published research

Niagen® is supported by 30+ clinical studies demonstrating its safety and efficacy. These human studies form the foundation of our scientific evidence. Over 65% of registered ongoing or completed nicotinamide riboside trials use Niagen®.**

Partnership with 200+ institutions: We partner with top institutions like Mayo Clinic, National Institute on Aging, Harvard, and Cambridge.

Backed by independent research: 94% of Niagen® studies are independently peer-reviewed.
View studies and publications
A clinical trial published in Nature Communications 2016

The study shows that nicotinamide riboside (NR) is orally bioavailable in mice and humans, increasing NAD+ levels and identifying NAAD as a key biomarker of increased NAD+ metabolism.

A clinical trial published in The American Journal of Clinical Nutrition in 2017

This study found that oral nicotinamide riboside (NR) increases blood NAD+ levels in healthy volunteers, suggesting potential therapeutic benefits for conditions involving mitochondrial dysfunction.

A clinical trial published in Nature Communications in 2018

Martens et al., 2018 This study found that nicotinamide riboside (NR) is safe, increases NAD+ levels, and may improve heart health by lowering blood pressure and arterial stiffness.

A clinical trial published in The American Journal of Clinical Nutrition in 2018

Dollerup et al., 2018 This study found that 12 weeks of nicotinamide riboside (NR) supplementation at 2000 mg/day is safe but does not improve insulin sensitivity or whole-body glucose metabolism in obese, insulin-resistant adults.

A clinical trial published in Nature Communications in 2019

Conze et al., 2019 This study found that long-term supplementation of nicotinamide riboside (NR) up to 1000 mg/day in healthy overweight adults is safe, well-tolerated, and dose-dependently increases blood NAD+ levels without affecting cholesterol levels.

A clinical trial published in The American Journal of Clinical Nutrition in 2019

Elhassan et al., 2019 This study found that nicotinamide riboside (NR) supplementation in aged humans increases the skeletal muscle NAD+ levels, downregulates energy metabolism pathways, and reduces circulating inflammatory cytokines, indicating anti-inflammatory effects without altering muscle mitochondrial bioenergetics.

A clinical trial published inThe American Journal of Clinical Nutrition in 2020

Remie et al., 2020 This study found that 6 weeks of nicotinamide riboside (NR) supplementation increased muscle NAD+ metabolites and fat-free mass in overweight or obese individuals, but had no effect on insulin sensitivity or mitochondrial function.

A clinical trial published in The Journal of Physiology in 2021

Stocks et al., 2021 This study found that 7 days of nicotinamide riboside (NR) supplementation did not affect whole-body metabolism, skeletal muscle mitochondrial function, or exercise-induced metabolic responses in humans, despite increasing certain NAD+ metabolites in muscle.

A clinical trial published in Science Advances in 2023

Lapatto et al., 2023 This study found that long-term nicotinamide riboside (NR) supplementation in BMI-discordant twins boosted NAD+ metabolism, increased muscle mitochondria and stem cell function, and improved gut bacteria.

A clinical trial published in the journal of Magnetic Resonance in Medicine in 2024

Nanga et al., 2024 This study found that acute supplementation of nicotinamide riboside (NR) significantly increased NAD+ levels in the human brain, as measured by downfield proton MRS, confirming NR's potential to boost cerebral NAD+ concentrations in healthy individuals.

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Third-party verification for your health

We employ rigorous quality testing to support your health. Our science-backed supplements are routinely assessed by third-party testers for quality, safety, and potency.
Learn more
Alkemist Assured™ Transparency Program

We partner with Alkemist Labs for the third-party testing of our products. Alkemist champions transparency, and provides their own consumer-friendly certificates of analysis on a regular basis as they continually test our products.

An Alkemist Assured seal confirms that Tru Niagen is verified and backed with potency and purity confirmation testing services for raw material and blended ingredient quality.

A minimum one year commitment is required for each product in the program in order to be permitted to use the Alkemist Assured™ seal.

Verified for Potency and Quality

We’ve built our reputation on quality, safety, and unmatched transparency. Tru Niagen® goes through extensive testing to ensure purity and potency, with each batch verified by leading third-party labs.

You can trust that every product meets the highest standards, and we make it easy for you to verify. Head to our Quality page to access your product’s certificate of analysis for full transparency on the quality you’re getting in every bottle.

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Backed by 25 years of research & innovation

30+

Human Clinical Studies

Backed by peer-reviewed published studies.

2

Nobel Prize Winners

Endorsed by a Scientific Advisory Board of world-leading researchers.

50+

Patents

Backed by innovation gold standards in the supplement space.

400+

Published Scientific Studies

NR is well-researched in published preclinical and clinical studies.

Frequently Asked Questions

Our Complementary Products

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

**Based on registered ongoing or completed clinical trials under "nicotinamide riboside" on clinicaltrials.gov.

***Based on the top selling dietary supplement brands by revenue per the largest U.S. ecommerce marketplace [identified through a search dated March 1, 2023 – Feb. 29. 2024 using “NAD precursors”]

†In combination with a healthy lifestyle.

‡In reference to physiological (not mental) stress.

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