Tru Niagen® 500mg—trusted by athletes, practitioners, and researchers. Shop here.

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The original NAD+ research brand

Increase NAD+ with Niagen® NR. 40+ studies. 25+ years of science. One patented ingredient.

Discover Tru Niagen

Backed by 25 years of research & innovation

For 25 years, we have been at the forefront of cellular science, contributing to discoveries that support your ability to live well.

40+

Human Clinical Studies

50+

Patents

500+

Published Scientific Studies

300+

Global Research Collaborations

Discover the best NAD-boosting solution for you

A bottle of Tru Niagen supplement with 300mg dosage, featuring a blue label and white cap.
A bottle of Tru Niagen supplement with 300mg dosage, featuring a blue label and white cap. It also shows the blue carton packaging the bottle comes in.
Best Seller

Tru Niagen® 300mg

The original - our minimum daily recommended serving

Capsule

From $50.40 $63.00

TRU NIAGEN 500mg supplement bottle with blue and silver design on a white background.
Hand holding a bottle of TRU NIAGEN 500mg supplement
New

Tru Niagen® 500mg

Originally exclusive to physicians and elite athletes. Upgrade to a higher, clinically researched serving per capsule.

Capsule

From $72.00 $90.00

A blue bottle of TRU Niagen supplement with white and light blue label, containing 120 capsules for daily NAD+ support.
A blue bottle of TRU Niagen supplement with white and light blue label, containing 120 capsules for daily NAD+ support. It also features the blue carton packaging the products comes in.

Tru Niagen® 150mg

Our lowest starter serving for those who prefer a smaller capsule.

Capsule

From $88.00 $110.00

Line chart showing that NAD+ levels in tissue decline by up to 65% between ages 30 and 70. The graph curves downward from age 30 to age 70, indicating a steady decrease. Text on the chart reads “NAD+ Decline ↓ 65%.” Source: Massudi et al., 2012; Janssens et al., 2022, based on analysis of human skin and muscle tissue.

THE SCIENCE BEHIND NAD+

Every cell in your body is fueled by NAD+

Your 37.2 trillion cells are powered by NAD+, a vital coenzyme that fuels cellular energy and repair throughout your entire body. NAD+ levels naturally decline with age and lifestyle stressors. Replenishing NAD+ levels is essential for maintaining your cellular health, energy, and vitality.

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MEET OUR STAR SUPERNUTRIENT

The #1 NAD+ booster**

Discover Tru Niagen, a supplement backed by decades of research and clinically shown to increase blood NAD+ levels, supporting your cellular health.

Powered by Niagen®, our patented form of nicotinamide riboside, Tru Niagen is a well-researched and efficient NAD+ precursor, helping you maintain your health.

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Small daily choices. Big long-term benefits.

Lock in 20% savings and stay consistent. Subscribe now.

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Backed by world-leading researchers

"Niagen, Niagen Bioscience’s patented nicotinamide riboside product, is one of the most well-studied, carefully controlled dietary supplements, and indeed, a gold standard in the industry."

Roger Kornberg, Ph.D.
Nobel Prize Winner in Chemistry and Niagen Bioscience Scientific Advisory Board Chairman

"Tru Niagen stands out as the leading, gold-standard NAD+ supplement... crucial for maintaining cellular resilience, energy metabolism, and overall cellular repair. Further, it features patented nicotinamide riboside (NR), which is the most efficient NAD+ precursor available."

Dr. Jim LaValle
Clinical Pharmacist, CEO of Metabolic Code Enterprises, and former Niagen Bioscience Consultant

"Disturbances in NAD+ coenzymes can leave tissues unable to repair themselves, generate energy, and perform their normal homeostatic functions. In many conditions of metabolic stress, the genes that convert NR to NAD+ are up-regulated, which provides unique value over all other NAD+ precursors."

Charles Brenner, Ph.D., ChromaDex’s Chief Scientific Advisor
Alfred E Mann Family Foundation Chair in Diabetes and Cancer Metabolism at City of Hope National Medical Center

"With the clear preclinical benefits of NR observed in the brains of mice, I look forward to future clinical trial findings from testing in human subjects. In the meantime, the known ability of NR to enhance mitochondrial function and cellular energy makes it a top choice for my personal daily regimen."

Dr. Rudolph Tanzi
Kennedy Professor of Neurology, Harvard University Director, Genetics and Aging Research Unit, Massachusetts General Hospital

Take it from our Tru Believers

"It's made all the difference in the world. In every aspect of my health… I feel better now at 70 than I did at 50. Seriously."
– Iris, 70 years old, Verified Customer
"I feel like I am getting my youth back… I can actually feel it working. I’m an active trail runner, skateboarder, snowboarder, and mom, and take 2 Tru Niagen capsules daily."
- Verified Amazon Customer
"I was skeptical at first but I gave this product a month of use; then a month without to really make sure that the feeling I had was not a placebo of any sort! Happy to say I was able to tell difference ASAP... I felt great."
- Jeremiah Thomas, Verified Customer
“I am 66 and my wife and I have taken Niagen for 10 years and are both physically in better shape now than when we started. We see many people our age who are starting to decline and feel that we are not seeing that in our own lives. The Niagen experiment is working for us and we have no plans of stopping.”
- Kelly C, 66 years old, Verified Customer
“I have been taking this product for about a year and a half, and I have to say it has given my quality of life a big boost! What a difference it makes for me.”
- Lisa M., Verified Customer
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

**Based on registered ongoing or completed clinical trials under "nicotinamide riboside" on clinicaltrials.gov.

***Based on the top selling dietary supplement brands by revenue per the largest U.S. ecommerce marketplace [identified through a search dated Jan. 1, 2024 – Dec. 31, 2024 using “NAD precursors”]

†In combination with a healthy lifestyle.

‡In reference to physiological (not mental) stress.

§For use beyond 12 weeks, consult a health care professional.